• Membrane models for molecular simulations of peripheral membrane proteins 

      Moqadam, Mahmoud; Tubiana, Thibault Michel Joseph; Moutoussamy, Emmanuel Edouard; Reuter, Nathalie (Journal article; Peer reviewed, 2021)
      Peripheral membrane proteins (PMPs) bind temporarily to the surface of biological membranes. They also exist in a soluble form and their tertiary structure is often known. Yet, their membrane-bound form and their ...
    • Specificity of Loxosceles α clade phospholipase D enzymes for choline-containing lipids: Role of a conserved aromatic cage 

      Moutoussamy, Emmanuel Edouard; Waheed, Qaiser; Binford, Greta J.; Khan, Hanif Muhammad; Moran, Shane M.; Eitel, Anna R.; Cordes, Matthew H.J.; Reuter, Nathalie (Journal article; Peer reviewed, 2022)
      Spider venom GDPD-like phospholipases D (SicTox) have been identified to be one of the major toxins in recluse spider venom. They are divided into two major clades: the α clade and the β clade. Most α clade toxins present ...
    • Standard Binding Free Energy and Membrane Desorption Mechanism for a Phospholipase C 

      Moutoussamy, Emmanuel Edouard; Khan, Hanif Muhammad; Roberts, Mary B; Gershenson, Anne; Chipot, Christophe; Reuter, Nathalie (Journal article; Peer reviewed, 2022)
      Peripheral membrane proteins (PMPs) bind temporarily to cellular membranes and play important roles in signaling, lipid metabolism, and membrane trafficking. Obtaining accurate membrane-PMP affinities using experimental ...